Available on an as needed basis, our topical formulation services are available from concept through clinical development. We offer particular expertise in topical product development of Rx, OTC and cosmetic products.

The Symbio formulation laboratory is centrally located in Fort Collins, Colorado. It is fully equipped with lab scale processing equipment, as well as product testing equipment and stability chambers. 

New and generic product development requires a phased step approach:

  • Define product characteristics
  • Pre-formulation/de-formulation
  • Formulation development & refinement
  • Product testing
  • CMC development
  • Technology transfer & scale-up

Examples of work done for sponsors:

  • Patent review: (various products/dosage forms:  topical, oral, optic, rectal, and vaginal) to determine feasibility and identify opportunities for new product development outside the scope of patent protection.

  • Formulation development: (various products/dosage forms:  topical, oral, and vaginal) of new, as well as generic formulations.  In some cases significant work to avoid patent infringement was required.  From deformulation to tech transfer/scale-up.

  • Technical review: (various products/dosage forms) of stability data, processing methods, excipient selection, test methods (physical, analytical, in vitro and in vivo). 

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21 Perry Street • Port Jefferson, NY 11777 • (631) 474-8531
Email: rpanico@symbioresearch.com