Articles

CLINICAL TRIAL SPOTLIGHT

Trends in Atopic Dermatitis: Treatments and Trial Design

October 10, 2024

The last two years have seen a surge in proposed and initiated clinical trials for atopic dermatitis (AD), or eczema.

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REGULATORY SPOTLIGHT

Insights into Annex XVI – Article 3 of 3: “Prerequisites for a Clinical Investigation of Medical Devices without a Medical Purpose”

July 24, 2024

Are you planning a clinical investigation in the complex landscape of medical device regulations, particularly concerning products without a medical purpose (Annex XVI, REGULATION (EU) 2017/745 (MDR)?

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REGULATORY SPOTLIGHT

Insights into Annex XVI – Article 2 of 3: “Clinical Investigations of Medical Devices without a Medical Purpose”

June 21, 2024

Are you navigating the complex landscape of Medical Device Regulations (MDR) concerning products without a medical purpose (Annex XVI, MDR)? Symbio can help!

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REGULATORY SPOTLIGHT

Insights into Annex XVI – Article 1 of 3: “Designing the Investigator’s Brochure”

June 5, 2024

This article highlights the “guidance on content of the Investigator's Brochure for clinical investigations of medical devices - MDCG 2024-5,” recently published by the Medical Device Coordination Group (MDCG). The guideline is helpful in creating the Investigator's Brochure, a key document in the submission package to NCAs, and helps avoid queries in the submission process.

This guideline is also applicable for products listed in Annex XVI of REGULATION (EU) 2017/745-Medical Device Regulation (MDR). Annex XVI lists products without an intended medical purpose which are nevertheless covered by MDR.

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