Exciting News From Symbio | Proinnovera


Symbio & Dow Group merges with Proinnovera to form leading dermatology CRO, Symbio Proinnovera

New York, USA & Münster, Germany – November 16, 2023

The newly announced merger of NY-headquartered Symbio LLC and CA-headquartered Dow Development Laboratories LLC with Munster (Germany)-based Proinnovera will form Symbio Proinnovera, creating one of the world’s largest specialized dermatology-focused clinical
research organizations.

Founded over 20 years ago, the Symbio & Dow Group has a full-service clinical trial CRO offering for dermatology, complemented by a business active in the pre-clinical formulation of topicals, providing its client’s dermatology and aesthetics services – from pre-clinical formulation work to subsequent clinical trial execution.

Proinnovera was founded 25 years ago and is a leading European CRO in the dermatology clinical trial space. It is a full-service CRO conducting clinical studies from Phase I to IV, as well as non-interventional and medical device studies. Proinnovera turns study data into oversight for clients to accelerate decision-making, increasing transparency and efficiency in the conduct of clinical trials.

Both companies are proven market leaders among specialty dermatology CROs with exceptional geographical coverage. Their combined strength will enable them to excel at addressing customers’ needs and expectations in all areas of research.

The newly formed organization will leverage the combined power of two highly experienced teams with deep expertise in the dermatology space to generate efficiencies and accelerate clinical research.

Symbio President Rich Panico – who will become CEO of Symbio Proinnovera – commented, “I am more than excited to run what will be the leading dermatology CRO in our industry. I have always thought of Symbio and Proinnovera as not only mirror businesses on different continents but also as companies sharing common values. In fact, we wanted this partnership to happen 5 years ago. It took longer than expected but I am so thrilled it has finally happened.”

Proinnovera Founder and CEO Dr Burkhard Breuer added, “We are delighted to merge with the Symbio Group. Our entities are highly complementary in terms of services, customers, and geographical footprint; we are fully aligned and share the same ultimate objective to elevate clinical trials to the next level.” Dr Breuer will support the integration of the new organization.

Symbio Proinnovera will be supported in its growth by ARCHIMED, a leading investment firm focused exclusively on healthcare industries.

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AAD 2023 – An Event to Remember

Several members of our Symbio staff had the pleasure of attending this year’s AAD conference in New Orleans. It was an amazing opportunity to connect with our clients in person and meet the companies and individuals responsible for driving innovation in dermatology.

We would like to express our gratitude to all of those who came to visit us, both at our booth and at our festive night at the House of Blues. We can’t wait to return to AAD next year in San Diego, and we are anxious to see all of our colleagues again!

Check out our photos and video below!

Symbio Releases White Paper: “Atopic Dermatitis – Considerations for Clinical Trials”

The newest white paper in Symbio’s white paper series was recently released entitled, “Atopic Dermatitis: Considerations for Clinical Trials.” This paper explores the clinical research challenges involved in AD trials including lack of standardized rating scales, the need to enroll children and young people, and the impact of time of year and geographic region.

Atopic dermatitis (AD), often called eczema, is a common and often debilitating skin condition whose root cause remains unknown but is likely to be related to allergies and immune dysregulation. No curative treatment exists for this condition and management usually consists of topical corticosteroids. In more severe cases, topical calcineurin inhibitors, biologics or immunosuppressants may be necessary. Unless remission occurs, AD is a chronic disease and needs to be suppressed through medication and vigorous hygiene practices.

AD’s prevalence, lack of cure, and impact on life quality have driven continuous research and investment into novel therapies. Unless an extremely tolerable and efficacious treatment becomes available, this trend is likely to continue.


Symbio Releases White Paper: “The Clinical State of Psoriasis”

Symbio has released their latest white paper “The Clinical State of Psoriasis” which aims to explain why biologics have become so popular and why their introduction has been so disruptive to classic topical drug studies.

Psoriasis is a common and often debilitating skin disease that affects millions of Americans each year. In the last few decades a variety of different pharmaceutical interventions have been brought to market with the intention of alleviating the suffering this ailment inflicts. These efforts have coalesced into two main classes of drugs: Topical medications and systemic treatments. These systemic, biologic treatments generally come from a newer class of drugs known as monoclonal antibodies, or MABs.

As the psoriasis market expands to include new systemic agents, clinical trials and their enrollment become increasingly complex. Due to the rise of treatment options such as biologics, topical psoriasis drugs have seen slow enrollment over the last decade


Success for Symbio at the 2022 AAD Annual Meeting

Symbio and Dow Development Laboratories exhibited at the 2022 AAD Annual Meeting from March 25 to March 29 at the Boston Convention & Exhibition Center in Boston, MA. The event was a huge success for all. It was wonderful to see so many familiar faces and to make new connections.

View videos of AAD Annual Meeting at the Symbio Booth and our 20th Anniversary Dinner Celebration at SPIN.